Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3416
Gene Symbol: IDE
IDE
P14735 insulin degrading enzyme Enzyme 71 0.604 0.577 6.6E-03 0.200 None 1.000 1 0 2018 2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.500 None 1.000 11 0 2001 2017
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 159 0.529 0.808 1.00 0.500 None 1.000 4 0 2005 2017
Entrez Id: 841
Gene Symbol: CASP8
CASP8
Q14790 caspase 8 Enzyme 480 0.404 0.923 3.7E-06 0.200 None 1.000 3 0 2005 2017
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.500 None 1.000 3 0 2008 2017
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.500 None 1.000 3 0 2009 2017
Entrez Id: 9927
Gene Symbol: MFN2
MFN2
O95140 mitofusin 2 Enzyme 334 0.471 0.846 0.99 0.200 None 1.000 2 0 2017 2017
Entrez Id: 506
Gene Symbol: ATP5F1B
ATP5F1B
P06576 ATP synthase F1 subunit beta Transporter 62 0.626 0.654 0.98 0.200 None 1.000 1 0 2017 2017
Entrez Id: 522
Gene Symbol: ATP5PF
ATP5PF
P18859 ATP synthase peripheral stalk subunit F6 Transporter 26 0.716 0.538 6.1E-03 0.200 None 1.000 1 0 2017 2017
Entrez Id: 487
Gene Symbol: ATP2A1
ATP2A1
O14983 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 Transporter 46 0.682 0.423 1.5E-14 0.200 None 1.000 1 0 2017 2017
Entrez Id: 498
Gene Symbol: ATP5F1A
ATP5F1A
P25705 ATP synthase F1 subunit alpha Transporter 84 0.604 0.731 1.00 0.200 None 1.000 1 0 2017 2017
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.200 None 1.000 1 0 2017 2017
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.200 None 1.000 1 0 2017 2017
Entrez Id: 3454
Gene Symbol: IFNAR1
IFNAR1
P17181 interferon alpha and beta receptor subunit 1 Receptor 142 0.532 0.769 3.3E-12 0.200 None 1.000 1 0 2017 2017
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor Signaling 416 0.433 0.808 0.99 0.300 None 1.000 9 0 2004 2016
Entrez Id: 2539
Gene Symbol: G6PD
G6PD
P11413 glucose-6-phosphate dehydrogenase Enzyme 410 0.424 0.846 0.97 0.200 None 1.000 3 0 2006 2016
Entrez Id: 4023
Gene Symbol: LPL
LPL
P06858 lipoprotein lipase Enzyme 290 0.474 0.808 1.3E-09 0.200 None 1.000 2 0 2008 2016
Entrez Id: 2538
Gene Symbol: G6PC
G6PC
P35575 glucose-6-phosphatase catalytic subunit 132 0.560 0.692 1.8E-05 0.200 None 1.000 2 0 2005 2016
Entrez Id: 2597
Gene Symbol: GAPDH
GAPDH
P04406 glyceraldehyde-3-phosphate dehydrogenase Enzyme 305 0.447 0.808 0.11 0.200 None 1.000 1 0 2016 2016
Entrez Id: 27092
Gene Symbol: CACNG4
CACNG4
Q9UBN1 calcium voltage-gated channel auxiliary subunit gamma 4 Ion channel 5 0.839 0.346 1.7E-02 0.200 None 1.000 1 0 2016 2016
Entrez Id: 2876
Gene Symbol: GPX1
GPX1
P07203 glutathione peroxidase 1 Enzyme 290 0.458 0.923 3.9E-05 0.500 None 1.000 5 0 2004 2015
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.200 None 1.000 4 0 2006 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.500 None 1.000 3 0 2011 2015
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
P17936 insulin like growth factor binding protein 3 Enzyme modulator 350 0.439 0.808 0.91 0.200 None 1.000 2 0 2007 2015
Entrez Id: 8660
Gene Symbol: IRS2
IRS2
Q9Y4H2 insulin receptor substrate 2 152 0.535 0.654 0.99 0.500 None 1.000 2 0 2010 2015